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156706-72-8

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156706-72-8 Structure

156706-72-8 Structure
IdentificationBack Directory
[Name]

N6-DiMethylaMinoMethylidene isoguanosine
[CAS]

156706-72-8
[Synonyms]

N6-DiMethylaMinoMethylidene isoguanosine
N-[(Dimethylamino)methylene]-1,2-dihydro-2-oxoadenosine
Adenosine, N-[(dimethylamino)methylene]-1,2-dihydro-2-oxo- (9CI)
[Molecular Formula]

C13H18N6O5
[MDL Number]

MFCD25542456
[MOL File]

156706-72-8.mol
[Molecular Weight]

338.32
Chemical PropertiesBack Directory
[density ]

1.774±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka]

8.129±0.40(predicted)
Hazard InformationBack Directory
[Uses]

N6-Dimethylaminomethylidene isoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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