| Identification | Back Directory | [Name]
THP-PEG6 | [CAS]
146395-14-4 | [Synonyms]
THP-PEG6
THP-PEG5-OH
OH-PEG5-THP
CAS_146395-14-4
THP-PEG5-alcohol
3,6,9,12-Tetraoxatetradecan-1-ol, 14-[(tetrahydro-2H-pyran-2-yl)oxy]- | [Molecular Formula]
C15H30O7 | [MDL Number]
MFCD26793753 | [MOL File]
146395-14-4.mol | [Molecular Weight]
322.39 |
| Hazard Information | Back Directory | [Description]
THP-PEG7 is a PEG linker containing a THP protecting group and a hydroxyl group. THP is acid labile and is commonly used for the protection of alcohol groups. The terminal hydroxyl group can be further reacted to derivatize the compound. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media. | [Uses]
THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
Henan Alfachem Co.,Ltd.
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| Tel: |
0371-55051623 18137891487 |
| Website: |
www.chemicalbook.com/supplier/14555231/ |
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