| Identification | More | [Name]
(RS)-MCPG | [CAS]
146669-29-6 | [Synonyms]
(+/-)-ALPHA-METHYL-(4-CARBOXYPHENYL)GLYCINE
[+/-]-MCPG
(RS)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE
(RS)-A-METHYL-4-CARBOXYPHENYLGLYCINE
(RS)-MCPG
(+/-)MCPG
(+/-)-A-METHYL-(4-CARBOXYPHENYL)GLYCINE
(+-)-A-METHYL-4-CARBOXYPHENYLGLYCINE MET ABOTROPIC GLUTAMAT | [Molecular Formula]
C10H11NO4 | [MDL Number]
MFCD00210205 | [Molecular Weight]
209.2 | [MOL File]
146669-29-6.mol |
| Chemical Properties | Back Directory | [Boiling point ]
425.3±40.0 °C(Predicted) | [density ]
1.390±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
DMSO : 6 mg/mL (28.68 mM; Need ultrasonic and warming) | [form ]
Powder | [pka]
1.76±0.10(Predicted) | [color ]
White | [InChI]
1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15) | [InChIKey]
DNCAZYRLRMTVSF-UHFFFAOYSA-N | [SMILES]
CC(N)(C(O)=O)c1ccc(cc1)C(O)=O | [CAS DataBase Reference]
146669-29-6(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
(RS)-MCPG is a non-selective group I/group II metabotropic glutamate receptor antagonist. | [Biological Activity]
Non-selective group I/group II metabotropic glutamate receptor antagonist. See (S)-isomer ((S)-a-Methyl-4-carboxyphenylglycine ). | [in vivo]
(RS)-MCPG (alpha-MCPG; 500 μM) blocks the TBS-induced shifts in EGABA in either juvenile or neonatal neurons[1].
Pretreatment with the low dose of (RS)-MCPG (25 nM; i.c.; daily; 5 days) significantly attenuates amphetamine-induced locomotor activity in 10-day-old male and female rats of Sprague-Dawley descent[2].
| [IC 50]
mGluR | [storage]
Room temperature |
|
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