| Identification | More | [Name]
Ethyl diethoxyphosphinylformate | [CAS]
1474-78-8 | [Synonyms]
DIETHOXYPHOSPHINYLFORMIC ACID ETHYL ESTER
(ETHOXYCARBONYL)PHOSPHONIC ACID DIETHYL ESTER
ETHYL DIETHOXYPHOSPHINYLFORMATE
TRIETHYL PHOSPHONOFORMATE
Diethyl carbethoxyphosphonate
Diethyl ethoxycarbonylphosphonate
Ethyl diethoxyphosphinecarboxylate oxide
Formic acid, phosphono-, triethyl ester
phosphinecarboxylicacid,diethoxy-,ethylester,oxide
Triethyl carboxyphosphonate
Triethyl phosphonomethanoate
TRIETHYL PHOSPHONOFORMATE 98%
PhosphonoformicacidTriethylester
TRIETHYL PHOSPHONOFORMATE (ETHYL DIETHOXYPHOSPHINILFORMATE)
ethyl diethyl-phosphonoformate
ETHYL DIETHOXYPHOSPHINYLFORMATE (TRIETHYL PHOSPHONOFORMATE) | [EINECS(EC#)]
216-016-8 | [Molecular Formula]
C7H15O5P | [MDL Number]
MFCD00009108 | [Molecular Weight]
210.16 | [MOL File]
1474-78-8.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S36/37:Wear suitable protective clothing and gloves .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29319019 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to slightly yellow liquid | [Uses]
Diethyl (Ethoxycarbonyl)phosphonate is an impurity in the synthesis of Foscarnet (F727400), an inhibitor of viral DNA polymerase and reverse transcriptase. Foscarnet is used as an antiviral. | [General Description]
for synthesis | [Purification Methods]
Dissolve it in Et2O, shake this with H2O (to remove any trace of NaCl impurity), dry (Na2SO4), evaporate and distil it using an efficient fractionating column. [Nylén Chem Ber 57 1035 1924, Reetz et al. J Am Chem Soc 77 3813 1955, Monson Advanced Organic Synthesis Academic Press p 89 1972, Beilstein 3 II 103.] |
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