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1479071-34-5

1479071-34-5 Structure

1479071-34-5 Structure
IdentificationBack Directory
[Name]

2-Cyano-N,N-dimethyl-3-(2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-10-yl)-2-propenamide
[CAS]

1479071-34-5
[Synonyms]

GSHtracer
2-Cyano-N,N-dimethyl-3-(2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-10-yl)-2-propenamide
[Molecular Formula]

C21H21N3O3
[MOL File]

1479071-34-5.mol
[Molecular Weight]

363.41
Chemical PropertiesBack Directory
[Boiling point ]

647.9±55.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

5.29±0.40(Predicted)
[color ]

Brown to reddish brown
[InChI]

1S/C21H21N3O3/c1-23(2)20(25)16(12-22)11-15-10-14-9-13-5-3-7-24-8-4-6-17(18(13)24)19(14)27-21(15)26/h9-11H,3-8H2,1-2H3/b16-11+
[InChIKey]

YCXQIYZKBAKCHQ-LFIBNONCSA-N
[SMILES]

O=C1OC2=C3C4=C(CCCN4CCC3)C=C2C=C1/C=C(C#N)/C(N(C)C)=O
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

GSHtracer is a fluorescent probe for measuring of glutathione (GSH) levels.

[Uses]

GSHtracer is a ratiometric probe for measuring of GSH levels. GSHtracer exhibits Ex/Em from 520/580 nm to 430/510 nm (upon GSH binding) [1].
[Biological Activity]

GSHtracer is a real-time probe monitoring of GSH (reduced glutathione) dynamics and heterogeneity.
[storage]

Store at -20°C
[References]

[1] Eui Man Jeong, et al. Real-Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function. Stem Cell Reports. 2018 Feb 13;10(2):600-614. DOI:10.1016/j.stemcr.2017.12.007
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