| Identification | Back Directory | [Name]
1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine | [CAS]
1480833-70-2 | [Synonyms]
PF-04885614
2-(4-(4-(Trifluoromethoxy)phenyl)-1H-imidazol-2-yl)propan-2-amine
1-Methyl-1-[4-(4-trifluoromethoxy-phenyl)-1H-imidazol-2-yl]-ethylamine
PF04885614,neurodevelopmental,neurological,PF-04885614,ion,Inhibitor,inhibit,Na+ channels,Sodium Channel,channel,PF 04885614,diseases,Na channels | [Molecular Formula]
C13H14F3N3O | [MDL Number]
MFCD26792589 | [MOL File]
1480833-70-2.mol | [Molecular Weight]
285.265 |
| Chemical Properties | Back Directory | [Boiling point ]
414.6±45.0 °C(Predicted) | [density ]
1.293±0.06 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
<28.53mg/ml in DMSO; <28.53mg/ml in ethanol | [form ]
Solid | [pka]
13.83±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
PF-04885614 is a potent NaV1.8 inhibitor, extracted from patent US2018328915. PF-04885614 has potential for neurological and neurodevelopmental diseases treatment[1]. | [Biological Activity]
PF-04885614 is a potent and selective Nav1.8 inhibitor. | [storage]
Store at -20°C | [References]
[1] Brady MAHER, et al. Treatment of Neurological and Neurodevelopmental Diseases and Disorders Associated with Aberrant Ion Channel Expression and Activity. US20180328915A1. |
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