| Identification | More | [Name]
3-BENZYLOXYANILINE | [CAS]
1484-26-0 | [Synonyms]
3-BENZYLOXYANILINE
AKOS BBB/398
AKOS BC-2549
M-(BENZYLOXY)ANILINE
TIMTEC-BB SBB000388
Benzenamine, 3-(phenylmethoxy)-
3-Aminophenyl benzyl ether
3-(benzyloxy)phenylamine
3-(Phenylmethoxy)aniline | [EINECS(EC#)]
216-056-6 | [Molecular Formula]
C13H13NO | [MDL Number]
MFCD00007784 | [Molecular Weight]
199.25 | [MOL File]
1484-26-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Beige to tan powder | [Melting point ]
63-67 °C (lit.) | [Boiling point ]
170 °C(Press: 3 Torr) | [density ]
1.129±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
soluble in Methanol | [form ]
Solid | [pka]
4.17±0.10(Predicted) | [color ]
Pale brown | [InChI]
InChI=1S/C13H13NO/c14-12-7-4-8-13(9-12)15-10-11-5-2-1-3-6-11/h1-9H,10,14H2 | [InChIKey]
IGPFOKFDBICQMC-UHFFFAOYSA-N | [SMILES]
C1(N)=CC=CC(OCC2=CC=CC=C2)=C1 | [CAS DataBase Reference]
1484-26-0(CAS DataBase Reference) | [EPA Substance Registry System]
3-(Benzyloxy)aniline (1484-26-0) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
2811 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29222990 |
| Hazard Information | Back Directory | [Chemical Properties]
Beige to tan powder | [Synthesis Reference(s)]
Tetrahedron Letters, 23, p. 147, 1982 DOI: 10.1016/S0040-4039(00)86770-2 | [Synthesis]
Using 1-(benzyloxy)-3-nitrobenzene as the starting material, the reaction was carried out using an experimental method similar to that of Example 59, in which ferrous acetate (II), nickel nitrate (II), or cobalt acetylacetonate (III) was chosen as the metal reducing agent. The experimental results are detailed in Table 11. The data of Examples 60 to 66 show that the reaction rate is significantly enhanced when metal compounds such as iron, nickel or cobalt salts and amine additives such as pyrrolidine are added to the catalytic reduction system of the present invention in the presence of a rhodium/carrier catalyst. Under this condition, functional groups such as benzyl ether, which are easy to reduce, are retained, and nitro is selectively reduced to amino, thereby increasing the yield of the target products 3-benzyloxyaniline and 3-aminophenol. | [References]
[1] Patent: EP1541582, 2005, A1. Location in patent: Page/Page column 45
[2] Patent: EP1541582, 2005, A1. Location in patent: Page/Page column 45
[3] Patent: EP1541582, 2005, A1. Location in patent: Page/Page column 45
[4] Patent: EP1541582, 2005, A1. Location in patent: Page/Page column 45
[5] Patent: EP1541582, 2005, A1. Location in patent: Page/Page column 45 |
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