| Identification | Back Directory | [Name]
2-Benzoxazolamine, N-[(1R)-2-cyclohexyl-1-(2-pyridinyl)ethyl]-5-methyl- | [CAS]
149106-77-4 | [Synonyms]
BIRM 271
2-Benzoxazolamine, N-[(1R)-2-cyclohexyl-1-(2-pyridinyl)ethyl]-5-methyl- | [Molecular Formula]
C21H25N3O | [MOL File]
149106-77-4.mol | [Molecular Weight]
335.44 |
| Hazard Information | Back Directory | [Uses]
(R)-Ontazolast ((R)-BIRM-270) is a potent inhibitor of leukotriene biosynthesis, effectively blocking the release of arachidonic acid and demonstrating an impressive IC50 value of 0.001 microM in human polymorphonuclear leukocytes. | [References]
[1] Benzoxazolamines and benzothiazolamines: potent, enantioselective inhibitors of leukotriene biosynthesis with a novel mechanism of action |
|
|