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149725-15-5

149725-15-5 Structure

149725-15-5 Structure
IdentificationBack Directory
[Name]

LY 806303
[CAS]

149725-15-5
[Synonyms]

L806303
L-806303
L 806303
LY 806303
[Molecular Formula]

C16H14O5S
[MDL Number]

MFCD00113711
[MOL File]

149725-15-5.mol
[Molecular Weight]

318.348
Hazard InformationBack Directory
[Description]

LY 806303 is a potent & highly selective inhibitor of thrombin.
[Uses]

LY 806303 is a potent and selective inhibitor of human α-thrombin. LY 806303 specifically acylates Ser-205 within the catalytic triad of α-thrombin on the heavy chain and a key site involved in the enzymatic activity of thrombin. The mechanism of action of LY 806303 as an enzyme inhibitor is through the specific acylation of this catalytic serine residue[1].
[References]

[1] Characterization of the Interaction between Human a-Thrombin and Methyl 3-(2-Methyl-l-oxopropoxy)[ l]benzothieno[ 3,2-b]furan-2-carboxylate (LY806303) Using Electrospray Mass Spectrometry and Tandem Mass Spectrometry
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Company Name: TargetMol Chemicals Inc.
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