| Identification | Back Directory | [Name]
Elisartan | [CAS]
149968-26-3 | [Synonyms]
HN 65021 1H-Imidazole-5-carboxylic acid, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[(ethoxycarbonyl)oxy]ethyl ester | [Molecular Formula]
C27H29ClN6O5 | [MOL File]
149968-26-3.mol | [Molecular Weight]
553.01 |
| Chemical Properties | Back Directory | [Boiling point ]
745.0±70.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
4.16±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Elisartan is an orally active non-peptide pro-agent of angiotensin II AT1 receptor antagonist HN-12206, and shows anti-hypertension activities. | [IC 50]
AT1 Receptor | [References]
[1] J R Cockcroft, et al. The effect of HN-65021 on responses to angiotensin II in human forearm vasculature. Br J Clin Pharmacol. 1995 Dec; 40(6): 591–593. |
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