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Quipazine Dimaleate is a 5-HT receptor agonist. | [in vivo]
Quipazine dimaleate (2.5, 5 and 7.5 mg/kg, one dose for once; i.p.) affects dietary self-selection of different macronutrient diets in male and female rats[1]. | Animal Model: | Male and female Wistar rats feed with different sources of the three macronutrients (Group 1: casein, corn starch, safflower oil. Group 2: egg protein, corn starch/sucrose, lard. Group S: casein hydrolysate, maltose dextrin, butter.)[1] | | Dosage: | 2.5, 5 and 7.5 mg/kg | | Administration: | Intraperitoneal injection; 2.5, 5 and 7.5 mg/kg, one dose for once | | Result: | Increased water intake and food intake of male rats from Group S, and reduced food intake of female rats from Group 1 and Group 2s at 2h post-injection. Reduced food intake in female rats from Group 2, reduced protein intake in female rats from Group 1. |
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