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1510653-27-6

1510653-27-6 Structure

1510653-27-6 Structure
IdentificationBack Directory
[Name]

4,7,11,14-Tetraazaoctacosanamide, N-[2-[bis(2-hydroxytetradecyl)amino]ethyl]-16-hydroxy-14-(2-hydroxytetradecyl)-4,7-bis[3-[[2-[(2-hydroxytetradecyl)amino]ethyl]amino]-3-oxopropyl]-10-oxo-
[CAS]

1510653-27-6
[Synonyms]

G0-C14
4,7,11,14-Tetraazaoctacosanamide, N-[2-[bis(2-hydroxytetradecyl)amino]ethyl]-16-hydroxy-14-(2-hydroxytetradecyl)-4,7-bis[3-[[2-[(2-hydroxytetradecyl)amino]ethyl]amino]-3-oxopropyl]-10-oxo-
[Molecular Formula]

C106H216N10O10
[MOL File]

1510653-27-6.mol
[Molecular Weight]

1790.91
Chemical PropertiesBack Directory
[Boiling point ]

1429.4±65.0 °C(Predicted)
[density ]

0.975±0.06 g/cm3(Predicted)
[form ]

Oil
[pka]

14.11±0.20(Predicted)
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery[1][2].
[References]

[1] Li S, et al. Redox-responsive polyprodrug nanoparticles for targeted siRNA delivery and synergistic liver cancer therapy. Biomaterials. 2020 Mar;234:119760. DOI:10.1016/j.biomaterials.2020.119760
[2] Chen Q, et al. Biodegradable nanoparticles decorated with different carbohydrates for efficient macrophage-targeted gene therapy. J Control Release. 2020 Jul 10;323:179-190. DOI:10.1016/j.jconrel.2020.03.044
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