| Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2639634-80-1 | [Synonyms]
C14-4
C14-4 (C14-494,Lipid B-4)
C14-4 (C14-494,Lipid B-4,Lipid B4) | [Molecular Formula]
C84H173N5O7 | [MOL File]
2639634-80-1.mol | [Molecular Weight]
1365.3 |
| Chemical Properties | Back Directory | [Boiling point ]
1123.5±65.0 °C(Predicted) | [density ]
0.946±0.06 g/cm3(Predicted) | [solubility ]
Ethanol: 10 mg/ml | [form ]
Liquid | [pka]
14.41±0.20(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity[1]. | [References]
[1] Billingsley MM, et al. Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering. Nano Lett. 2020 Mar 11;20(3):1578-1589. DOI:10.1021/acs.nanolett.9b04246 |
|
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
www.chemicalbook.com/showsupplierproductslist927327/0_en.htm |
|