| Identification | Back Directory | [Name]
Vecabrutinib | [CAS]
1510829-06-7 | [Synonyms]
Vecabrutinib
Vecabrutinib(SNS-062)
[1,3'-Bipiperidine]-4'-carboxamide, 1'-(6-amino-5-fluoro-4-pyrimidinyl)-3-[[3-chloro-5-(trifluoromethyl)phenyl]amino]-2-oxo-, (3R,3'R,4'S)- | [Molecular Formula]
C22H24ClF4N7O2 | [MOL File]
1510829-06-7.mol | [Molecular Weight]
529.92 |
| Chemical Properties | Back Directory | [Boiling point ]
776.0±60.0 °C(Predicted) | [density ]
1.509±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (235.88 mM) | [form ]
Solid | [pka]
16.01±0.40(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
Vecabrutinib is used in biological studies of Burton’s Tyrosine Kinase (BTK) inhibitors. | [in vivo]
Vecabrutinib has good oral bioavailability in rat and dog (%F ≥ 40%) and a terminal half-life of 5 to 6 hours. Vecabrutinib is well tolerated with continuous drug levels and at exposures much greater than those achieved for PCI-32765[1]. |
|
| Company Name: |
Wuhan Topule
|
| Tel: |
+86-02787215551 +86-19945035818 |
| Website: |
http://www.topule.com/ |
|