| Identification | Back Directory | [Name]
BOC-L-2-AMINO-4-BROMO-4-PENTENOIC ACID | [CAS]
151215-34-8 | [Synonyms]
Boc-(S)-(2-bromoallyl)glycine
(S)-N-BOC-(2-BROMOALLYL)-GLYCINE
BOC-L-2-AMINO-4-BROMO-4-PENTENOIC ACID
BOC-L-2-AMINO-4-BROMO-4-PENTENOIC ACID USP/EP/BP
(S)-2-[(t-Butoxycarbonyl)amino]-4-bromo-4-pentenoic acid
(Tert-Butoxy)Carbonyl L-2-Amino-4-bromo-4-pentenoic acid
(S)-4-BroMo-2-((tert-butoxycarbonyl)aMino)pent-4-enoic acid
(2S)-4-bromo-2-{[(tert-butoxy)carbonyl]amino}pent-4-enoic acid
Boc-L-2-amino-4-bromo-4-pentenoic acid≥ 99% (HPLC, Chiral purity)
(2S)-4-bromo-2-[(2-methylpropan-2-yl)oxycarbonylamino]pent-4-enoicaci
(2S)-4-bromo-2-[(2-methylpropan-2-yl)oxycarbonylamino]pent-4-enoic acid
4-Pentenoic acid, 4-bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2S)- | [Molecular Formula]
C10H16BrNO4 | [MDL Number]
MFCD01320852 | [MOL File]
151215-34-8.mol | [Molecular Weight]
294.14 |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Synthesis]
4.3: After completion of the separation, the reaction mixture was extracted with ethyl acetate to remove the D-isomer to give L-2-amino-4-bromo-4-pentenoic acid. Subsequently, an aqueous solution of 5 L of acetone and 120 g of di-tert-butyl dicarbonate was added to the reaction system and the alkaline environment of the aqueous sodium carbonate solution was maintained. After the reaction was carried out for 5 hours, the reaction mixture was acidified with 3M hydrochloric acid and the product was extracted with ethyl acetate. The organic phase was dried and purified by crystallization to give 64 g of (S)-4-bromo-2-((tert-butoxycarbonyl)amino)pent-4-enoic acid as a solid. The purity of the product was 98.84% and the overall yield was 43.5% by HPLC analysis. | [References]
[1] Patent: CN107827767, 2018, A. Location in patent: Paragraph 0030; 0036
[2] Tetrahedron Letters, 1993, vol. 34, # 28, p. 4485 - 4488 |
|
| Company Name: |
Shanghai GL Peptide Ltd.
|
| Tel: |
+86-21-61263340; 17609490614 13764994101 |
| Website: |
https://www.chemicalbook.com/supplier/10480342/ |
|