| Identification | More | [Name]
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde | [CAS]
15186-48-8 | [Synonyms]
1,3-DIOXOLANE-4-CARBOXALDEHYDE, 2,2-DIMETHYL-, (R)-
(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXALDEHYDE
2,3-O-ISOPROPYLIDENE-D-GLYCERALDEHYDE
2,3-O-(R)-ISOPROPYLIDENE-L-GLYCERALDEHYDE
(4R)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBALDEHYDE
D-(R)-GLYCERALDEHYDE ACETONIDE
(R)-2,2-DIMETHYL-[1,3]DIOXOLANE-4-CARBALDEHYDE
(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXALDEHYDE
(R)-2,3-ISOPROPYLIDENE GLYCERALDEHYDE
R-(+)-Solketaldehyde
D-Glyceraldehyde-acetonide
R-Glyceraldehyde-acetonide
( R)-(+)-2,2-dimethyl-1,3-dioxolan-4-carboxaldehyde
(R)-(+)-2,2-Dimethyl-1,3-Dioxylane-4-Carboxadehyde
R-(+)-2,3-O-Isopropylidene-D-glyceraldehyd
(R)-(+)-2,2-Dimethyl-1,3-Dioxo
(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4
(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXALDEHYDE(INTERMEDIATEOFGEMCITABINE)
R-(+)-2,3-O-Isopropylidene-D-glyceraldehyde
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehydeDiscontined, Unstable | [EINECS(EC#)]
676-289-8 | [Molecular Formula]
C6H10O3 | [MDL Number]
MFCD00269682 | [Molecular Weight]
130.14 | [MOL File]
15186-48-8.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless Transparent Liquid | [alpha ]
53.8 º (c=2, CHCl3) | [Boiling point ]
139 °C (lit.) | [density ]
1.045 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.454(lit.)
| [Fp ]
143 °F
| [storage temp. ]
-20°C | [solubility ]
Difficult to mix. | [form ]
Liquid | [color ]
Colorless to Pale Yellow | [Optical Rotation]
[α]22/D +53.8°, c = 2 in chloroform | [InChI]
InChI=1S/C6H10O3/c1-6(2)8-4-5(3-7)9-6/h3,5H,4H2,1-2H3/t5-/m0/s1 | [InChIKey]
YSGPYVWACGYQDJ-YFKPBYRVSA-N | [SMILES]
O1C[C@H](C=O)OC1(C)C | [CAS DataBase Reference]
15186-48-8(CAS DataBase Reference) | [NIST Chemistry Reference]
Acetone D-glyceraldehyde(15186-48-8) |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless Transparent Liquid | [Uses]
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a reactant involved in organic reactions including:• ;Henry condensation reactions1• ;Synthesis of highly functionalized chiral aziridines2• ;Olefination of aldehydes3• ;C-H oxidations4• ;Aldol-type condensations5• ;Synthesis of hydrophilic pyrazine dyes for use as exogenous fluorescent tracer agents6• ;Hosomi-Sakurai reactions7
| [Synthesis]
Add 220g of dichloromethane, 23g of bisacetone-D-mannitol, 0.23g of 18-crown-6-ether, and 0.4g of TEMPO to the clean reactor.
0.4g, stirring and mixing well, then slowly lower the temperature to 10 ℃, began to drop the mass percentage of 10wt% of sodium |
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