| Identification | More | [Name]
2,3-Dimethoxybenzoic acid | [CAS]
1521-38-6 | [Synonyms]
2,3-DIMETHOXYBENZOIC ACID
2-VERATRIC ACID
AKOS 233-29
DIMETHOXYBENZOIC ACID,2,3-
O-VERATRIC ACID
RARECHEM AL BO 0026
2,3-dimethoxy-benzoicaci
Benzoic acid, 2,3-dimethoxy-
DIMETHOXYBENZOIC ACID,2,3-(RG) | [EINECS(EC#)]
216-188-4 | [Molecular Formula]
C9H10O4 | [MDL Number]
MFCD00002432 | [Molecular Weight]
182.17 | [MOL File]
1521-38-6.mol |
| Chemical Properties | Back Directory | [Appearance]
LIGHT BEIGE FINE CRYSTALLINE POWDER | [Melting point ]
120-122 °C (lit.) | [Boiling point ]
275.56°C (rough estimate) | [density ]
1.2481 (rough estimate) | [refractive index ]
1.4500 (estimate) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
5.310g/l slightly soluble | [form ]
Fine Crystalline Powder | [pka]
3.97±0.10(Predicted) | [color ]
Light beige | [Water Solubility ]
slightly soluble | [BRN ]
2210858 | [InChI]
InChI=1S/C9H10O4/c1-12-7-5-3-4-6(9(10)11)8(7)13-2/h3-5H,1-2H3,(H,10,11) | [InChIKey]
FODBVCSYJKNBLO-UHFFFAOYSA-N | [SMILES]
C(O)(=O)C1=CC=CC(OC)=C1OC | [LogP]
0.907 (est) | [CAS DataBase Reference]
1521-38-6(CAS DataBase Reference) | [NIST Chemistry Reference]
2,3-Dimethoxybenzoic acid(1521-38-6) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [RTECS ]
DG8598700
| [Hazard Note ]
Irritant | [HS Code ]
29189090 | [Storage Class]
11 - Combustible Solids | [Toxicity]
mouse,LD50,intraperitoneal,> 800mg/kg (800mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 196, Pg. 478, 1976. |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
1,2-Dimethoxybenzene-->Carbon dioxide-->Sodium-->Toluene | [Preparation Products]
methyl 2-(7-hydroxybenzofuran-3-yl)acetate-->2,3-DIMETHOXYANILINE-->6-Formyl-2,3-dimethoxybenzoic acid-->7-METHOXY-3(2H)-BENZOFURANONE-->1,3-BENZODIOXOLE-4-CARBOXYLIC ACID-->2,3,3',4'-TETRAMETHOXYBENZOPHENONE-->Hydrazine, (2,3-dimethoxyphenyl)--->2,3-DIMETHOXY-BENZOYL CHLORIDE |
| Hazard Information | Back Directory | [Chemical Properties]
LIGHT BEIGE FINE CRYSTALLINE POWDER | [Uses]
2,3-Dimethoxybenzoic acid is widely used as an intermediate in organic synthesis, its methoxy-substituted aromatic ring enables selective functionalization, making it useful in the preparation of more complex aromatic and heterocyclic derivatives. In addition, it is applied in material science research for the development of functionalized polymers and organic electronic materials, where its structural and electronic properties can influence conductivity, stability, and overall material performance. | [Synthesis]
The general procedure for the synthesis of 2,3-dimethoxybenzoic acid from o-anisidine and carbon dioxide is as follows: an o-o-metalation reaction was carried out according to the method described in Example 1, using different substrates and CO2 as an electrophilic reagent. | [References]
[1] Angewandte Chemie - International Edition, 2002, vol. 41, # 2, p. 340 - 343
[2] Patent: US6384273, 2002, B1. Location in patent: Page column 9 |
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