| Identification | Back Directory | [Name]
bequinostatin C | [CAS]
152175-74-1 | [Synonyms]
bequinostatin C
Benzo[a]naphthacene-2-carboxylic acid, 8,13-dihydro-1,7,9,11-tetrahydroxy-8,13-dioxo-3-pentyl- | [Molecular Formula]
C28H22O8 | [MOL File]
152175-74-1.mol | [Molecular Weight]
486.47 |
| Chemical Properties | Back Directory | [Boiling point ]
794.4±60.0 °C(Predicted) | [density ]
1.540±0.06 g/cm3(Predicted) | [solubility ]
DMSO: Slightly soluble; Methanol: Slightly soluble | [form ]
A solid | [pka]
2.76±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
Bequinostatin C is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC50 = 40 μg/ml for human GSTP1).1 | [Uses]
Bequinostatin C is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC50=40 μg/mL for human GSTP1). | [References]
1. Yamazaki, T., Tatee, T., Aoyama, T., et al. Bequinostatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12 J. Antibiot. (Tokyo) 46(8),1309-1311(1993). |
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