| Identification | Back Directory | [Name]
CYCLOCURCUMIN(P) | [CAS]
153127-42-5 | [Synonyms]
CYCLOCURCUMIN(P)
2,3-Dihydro-2-(4-hydroxy-3-methoxyphenyl)-6-[(1e)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-4H-pyran-4-one
4H-Pyran-4-one, 2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-6-[(1E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]- | [Molecular Formula]
C21H20O6 | [MDL Number]
MFCD07779147 | [MOL File]
153127-42-5.mol | [Molecular Weight]
368.38 |
| Chemical Properties | Back Directory | [Boiling point ]
571.9±50.0 °C(Predicted) | [density ]
1.352±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
9.66±0.35(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Cyclocurcumin is a potent p38α inhibitor. Cyclocurcumin shows antirheumatic, antivasoconstrictive and antioxidant activities[1][2][3]. | [Definition]
ChEBI: Cyclocurcumin is a diarylheptanoid. | [References]
[1] Fu M, et al. Cyclocurcumin, a curcumin derivative, exhibits immune-modulating ability and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. Int J Mol Med. 2017 May;39(5):1164-1172. DOI:10.3892/ijmm.2017.2926
[2] Kim K, et al. Cyclocurcumin, an Antivasoconstrictive Constituent of Curcuma longa (Turmeric). J Nat Prod. 2017 Jan 27;80(1):196-200. DOI:10.1021/acs.jnatprod.6b00331
[3] Li Y, et al. Antioxidant properties and free radical scavenging mechanisms of cyclocurcumin. New Journal of Chemistry, 2018, 42(15): 12698-12705. |
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