| Identification | Back Directory | [Name]
Cav 2.2 blocker 1 | [CAS]
1567335-29-8 | [Synonyms]
Cav 2.2 blocker 1
1H-Pyrazole, 5-(4-chlorophenyl)-1-(2-methoxyphenyl)-3-(tetrahydro-2,2,6,6-tetramethyl-2H-pyran-4-yl)- | [Molecular Formula]
C25H29ClN2O2 | [MDL Number]
MFCD32067922 | [MOL File]
1567335-29-8.mol | [Molecular Weight]
424.96 |
| Chemical Properties | Back Directory | [Boiling point ]
547.2±50.0 °C(Predicted) | [density ]
1.16±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 20.83 mg/mL (49.02 mM) | [form ]
Solid | [pka]
-0.67±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1]. | [References]
[1] Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783. DOI:10.1016/j.bmcl.2018.10.007 |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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