ChemicalBook--->CAS DataBase List--->156856-32-5

156856-32-5

156856-32-5 Structure

156856-32-5 Structure
IdentificationBack Directory
[Name]

Deoxyfusapyrone
[CAS]

156856-32-5
[Synonyms]

Deoxyfusapyrone
Deoxyfusapyrone DISCONTINUED
4H-Pyran-4-one, 3-(4-deoxy-β-xylo-hexopyranosyl)-2-hydroxy-6-[(3E,5E,8Z)-2-hydroxy-1,1,5,7,9,11-hexamethyl-3,5,8-heptadecatrien-1-yl]-
[Molecular Formula]

C34H54O8
[MDL Number]

MFCD28898500
[MOL File]

156856-32-5.mol
[Molecular Weight]

590.79
Chemical PropertiesBack Directory
[Boiling point ]

765.9±60.0 °C(Predicted)
[density ]

1.148±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
[form ]

A solid
[pka]

4.50±1.00(Predicted)
Hazard InformationBack Directory
[Description]

Deoxyfusapyrone is an α-pyrone fungal metabolite originally isolated from F. semitectum and has antifungal activity. It is active against C. neoformans, A. fumigatus, A. niger, and A. flavus human mycoses (MICs = 1.56-6.25 μg/ml). Deoxyfusapyrone is also active against a variety of filamentous fungi, but not yeast or the bacterium B. megaterium, in a disc assay.
[Uses]

Deoxyfusapyrone is a broad spectrum antifungal metabolite isolated from several Fusarium species, first reported in 1994. Deoxyfusapyrone exhibits low zoo-toxicity as evidenced by a lack of toxicity against Artemia salina and is a useful candidate for control of postharvest crop diseases. Like the related fusapyrone, its mechanism of action is unknown and its structure was revised in 2006.
[storage]

Store at -20°C
[References]

[1] CLAUDIO ALTOMARE. Biological Characterization of Fusapyrone and Deoxyfusapyrone, Two Bioactive Secondary Metabolites of Fusarium semitectum[J]. Journal of Natural Products , 2000, 63 8: 1131-1135. DOI: 10.1021/np000023r
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