| Identification | Back Directory | [Name]
PHENAZINE-1-CARBOXYLIC ACID | [CAS]
2538-68-3 | [Synonyms]
emr211
NSC 15851
nrrlb-1482
nrrlb-1576
Tubermycin B
ShenqinMycin
JACS-2538-68-3
Tubermycin (A,B)
1-Carboxyphenazine
Phenazinecarboxylic Acid
1-carboxylicacidphenazine
1-phenazinecarboxylicacid
Phenazine-α-carboxylic Acid
Phenazine-a-carboxylic acid
PHENAZINE-1-CARBOXYLIC ACID
Phenazinecarboxylic acid (6CI)
phenazine-alpha-carboxylicacid
Phenazine-1-carboxylic acid 93%
phenazine-1-carboxylic acid Solution, 100ppm
PHENAZINE-1-CARBOXYLIC ACID ISO 9001：2015 REACH
1-Carboxyphenazine, 1-Carboxydibenzo[b,e]pyrazine
Phenazine-1-carboxylic acid, X-PigMent, ShenqinMycin
Phenazine-1-carboxylic acid Solution in Methanol, 100μg/mL
Phenazinecarboxylicacid (6CI),NSC 15851,Phenazine-a-carboxylic acid,TuberMycin B | [Molecular Formula]
C13H8N2O2 | [MDL Number]
MFCD00185184 | [MOL File]
2538-68-3.mol | [Molecular Weight]
224.21 |
| Chemical Properties | Back Directory | [Melting point ]
242-244℃ | [Boiling point ]
494.6±10.0 °C(Predicted) | [density ]
1.431±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
2.15±0.30(Predicted) | [color ]
Brown to Orange-Brown | [InChI]
InChI=1S/C13H8N2O2/c16-13(17)8-4-3-7-11-12(8)15-10-6-2-1-5-9(10)14-11/h1-7H,(H,16,17) | [InChIKey]
JGCSKOVQDXEQHI-UHFFFAOYSA-N | [SMILES]
C1(C(O)=O)C2C(=NC3C(N=2)=CC=CC=3)C=CC=1 |
| Hazard Information | Back Directory | [Chemical Properties]
Brown Solid | [Uses]
A microorganism based antimicrobial with high efficiency, low toxicity and good environmental compatibility. A key effective component of the pesticide M18. | [Uses]
Tubermycin B (1-phenazinecarboxylic acid) is a simple phenazine produced by several species of Pseudomonas and Actinomycetes. Tubermycin B is a weakly active antibacterial compound that plays a role in the biocontrol of plant diseases by several Pseudomonas strains. Tubermycin B and related phenazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives. | [Definition]
ChEBI: An aromatic carboxylic acid that is phenazine substituted at C-1 with a carboxy group. | [Synthesis Reference(s)]
Journal of Medicinal Chemistry, 43, p. 1350, 2000 DOI: 10.1021/jm990423f | [in vivo]
Phenazine-1-carboxylic acid (2 and 3 μg/mL, added through E3 medium, single dose) significantly prevented V. anguillaruminfection in zebrafish embryos[4]. | Animal Model: | Zebrafish embryos infected with Vibrio anguillarum[4] | | Dosage: | 2 μg/mL and 3 μg/mL | | Administration: | Added through zebrafish embryo E3 medium, single dose | | Result: | Effectively inhibited V. anguillarum infection in zebrafish embryos and increased embryo hatching rate. |
| [storage]
Store at -20°C |
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