ChemicalBook--->CAS DataBase List--->1578249-76-9

1578249-76-9

1578249-76-9 Structure

1578249-76-9 Structure
IdentificationBack Directory
[Name]

Mal-C6-α-Amanitin
[CAS]

1578249-76-9
[Synonyms]

Mal-C6-α-Amanitin
Mal-C6-α-Amanitin
[Molecular Formula]

C55H78N12O17S
[MDL Number]

MFCD32263389
[MOL File]

1578249-76-9.mol
[Molecular Weight]

1211.34
Chemical PropertiesBack Directory
[Boiling point ]

1688.7±65.0 °C(Predicted)
[density ]

1.46±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

12.38±0.70(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

Mal-C6-α-Amanitin is a agent-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.
[IC 50]

Daunorubicins/Doxorubicins
[References]

[1] Brian Lannutti,et al. Ror1 antibody immunoconjugates. WO2018237335A1.
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