| Identification | Back Directory | [Name]
ME401 | [CAS]
1595129-71-7 | [Synonyms]
ME401
P110delta-IN-1
PWT143 (ME-401)
P110δ inhibitor 1
PWT143; PWT-143; PWT 143; ME-401; ME401; ME 401
1,3,5-Triazin-2-amine, N-[1,1-dimethyl-2-[2-(1-methyl-4-piperidinyl)phenyl]ethyl]-4-[2-(methylsulfonyl)-1H-benzimidazol-1-yl]-6-(4-morpholinyl)- | [Molecular Formula]
C31H40N8O3S | [MDL Number]
MFCD32067909 | [MOL File]
1595129-71-7.mol | [Molecular Weight]
604.77 |
| Chemical Properties | Back Directory | [Boiling point ]
803.2±75.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:26.67(Max Conc. mg/mL);44.1(Max Conc. mM) | [form ]
Solid | [pka]
8.97±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
P110δ-IN-1 is a potent and selective inhibitor of P110δ extracted from patent WO 2014055647 A1, with an IC50 of 8.4 nM[1]. | [References]
[1] S. David Brown , et al. (sulfinyl and sulfonyl benzimidazolyl) pyrimidines and triazines, pharmaceutical compositions thereof, and their use for treating proliferative diseases. WO2014055647A1 |
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