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160552-54-5

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160552-54-5 Structure

160552-54-5 Structure
IdentificationBack Directory
[Name]

4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
[CAS]

160552-54-5
[Synonyms]

GI138870X
GI-138870X
GI 138870X
Lamivudine EP Impurity G
Lamivudine sulfoxide, (R)-
Lamivudine EP Impurity H / R Sulfoxide
Lamivudine Impurity 8(Lamivudine EP Impurity H)
Lamivudine EP Impurity H (Lamivudine (3R)-Sulfoxide)
4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one-S-oxide
4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
2(1H)-Pyrimidinone, 4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-
2(1H)-Pyrimidinone,4-amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]- (9CI)
Lamivudine Impurit Ⅴ:4-amino-1-((2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one
Lamivudine Impurity Ⅴ 4-amino-1-[(2R,3R,5S)-2-(hydro xymethyl)-1,3-oxathiolan-5-yl] pyrimidin-2(1H)-one-S-oxide
[Molecular Formula]

C8H11N3O4S
[MDL Number]

MFCD23104278
[MOL File]

160552-54-5.mol
[Molecular Weight]

245.26
Chemical PropertiesBack Directory
[Boiling point ]

601.7±65.0 °C(Predicted)
[density ]

1.93±0.1 g/cm3(Predicted)
[pka]

13.46±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Lamivudine (R)-Sulfoxide (Lamivudine EP Impurity H) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
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