| Identification | Back Directory | [Name]
(2R-cis)-5-(4-aMino-2-oxo-1(2H)-pyriMidinyl)-1,3-oxathiolane-2-carboxylic Acid | [CAS]
173829-09-9 | [Synonyms]
LaMivudine Acid
Lamivudine EP IMP A
Lamivudine Carboxylic Impurity
Lamivudine EP Impurity A(2R,5S)Monomer
Lamivudine EP Impurity A (2R,5S-Isomer)
Lamivudine EP Impurity A (Lamivudine Acid)
Lamivudine Impurity 1(Lamivudine EP Impurity A)
Lamivudine Impurity Ⅰ
(Lamivudine-carboxylic acid)
Lamivudine EP Impurity A / Lamivudine Carboxylic Impurity
(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylic acid
(2S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylic acid
(2R-cis)-5-(4-aMino-2-oxo-1(2H)-pyriMidinyl)-1,3-oxathiolane-2-carboxylic Acid
1,3-Oxathiolane-2-carboxylic acid, 5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-, (2R,5S)-
Lamivudine Imp. A (EP): (2R-cis)-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid
Lamivudine ImpurityⅠ:(LaMivudine Acid)(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylic acid
Lamivudine Impurit Ⅰ:(LaMivudine Acid)(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylic acid
Lamivudine EP Impurity AQ: What is
Lamivudine EP Impurity A Q: What is the CAS Number of
Lamivudine EP Impurity A Q: What is the storage condition of
Lamivudine EP Impurity A Q: What are the applications of
Lamivudine EP Impurity A | [Molecular Formula]
C8H9N3O4S | [MOL File]
173829-09-9.mol | [Molecular Weight]
243.24 |
| Chemical Properties | Back Directory | [Melting point ]
>208°C (dec.) | [Boiling point ]
546.6±60.0 °C(Predicted) | [density ]
1.87±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, Refrigerator, Under Inert Atmosphere | [solubility ]
Dimethylformamide; Methanol | [form ]
Solid | [pka]
1.94±0.40(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic | [CAS DataBase Reference]
173829-09-9 |
| Hazard Information | Back Directory | [Uses]
Lamivudine Acid (Lamivudine EP Impurity A) is an impurity of Lamivudine (L172500). Impurity A per European Pharmacopoeia. | [Synthesis]
Preparation of lamivudine impurity A lamivudine acid: 100 ml of methanol-water solution (1:1) was added to a 250 ml round-bottomed flask, 50 ml of 25% aqueous sodium hydroxide solution was added, and 5S-cytosine-1’- 1,3-oxathiolane-2-carboxylic a |
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