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160625-24-1

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160625-24-1 Structure

160625-24-1 Structure
IdentificationBack Directory
[Name]

PEG3-bis-(ethyl phosphonate)
[CAS]

160625-24-1
[Synonyms]

PEG3-bis-(ethyl phosphonate)
Diethyl-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis-phosphonate
Phosphonic acid, P,P'-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis-, P,P,P',P'-tetraethyl ester
[Molecular Formula]

C16H36O9P2
[MDL Number]

MFCD00778113
[MOL File]

160625-24-1.mol
[Molecular Weight]

434.4
Chemical PropertiesBack Directory
[Boiling point ]

510.5±45.0 °C(Predicted)
[density ]

1.126±0.06 g/cm3(Predicted)
Hazard InformationBack Directory
[Description]

PEG3-bis-(ethyl phosphonate) is a PEG linker with two ethyl phosphonate end groups. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
[Uses]

PEG3-bis-(ethyl phosphonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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