| Identification | Back Directory | [Name]
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A | [CAS]
1609108-96-4 | [Synonyms]
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A | [Molecular Formula]
C63H91N9O16 | [MOL File]
1609108-96-4.mol | [Molecular Weight]
1230.45 |
| Chemical Properties | Back Directory | [Boiling point ]
1350.487±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.296±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
11.960±0.40(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a Spliceostatin (HY-16466) analog, and a drug-linker conjugates for ADC, consisting of ADC Cytotoxin Thailanstatin A (HY-129589) and cleavable ADC linker (MC-vc-PAB). MC-VC-PAB-Cyclohexanediamine-Thailanstatin A can be used for ADC synthesis[1]. | [References]
[1] Dirico KJ, et al. Preparation of spliceostatin analog antibody conjugates for cancer treatment. World Intellectual Property Organization, WO2014068443 A1. 2014-05-08. |
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