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1610414-00-0

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1610414-00-0 Structure

1610414-00-0 Structure
IdentificationBack Directory
[Name]

EC1167
[CAS]

1610414-00-0
[Synonyms]

EC1167
[Molecular Formula]

C33H45N7O17S
[MDL Number]

MFCD32201134
[MOL File]

1610414-00-0.mol
[Molecular Weight]

843.81
Chemical PropertiesBack Directory
[Boiling point ]

1396.7±65.0 °C(Predicted)
[density ]

1.491±0.06 g/cm3(Predicted)
[pka]

2.80±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

EC1167 is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC)[1].
[References]

[1] Leamon CP, et al. Prostate-Specific Membrane Antigen-Specific Antitumor Activity of a Self-Immolative Tubulysin Conjugate. Bioconjug Chem. 2019 Jun 19;30(6):1805-1813. DOI:10.1021/acs.bioconjchem.9b00335
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