| Identification | Back Directory | [Name]
CAY10685 | [CAS]
1613116-16-7 | [Synonyms]
CAY10685
CAY10685,CAY-10685
CAY10685 Exclusive
Cyclopentanone, 2-[4-(4-chlorophenyl)-2-thiazolyl]-2-(2-propyn-1-yl)hydrazone | [Molecular Formula]
C17H16ClN3S | [MOL File]
1613116-16-7.mol | [Molecular Weight]
329.85 |
| Chemical Properties | Back Directory | [Boiling point ]
481.4±55.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 10 mg/ml; DMF:PBS(pH7.2) (1:2): 0.3 mg/ml; DMSO: 5 mg/ml; Ethanol: 3 mg/ml | [form ]
A crystalline solid | [pka]
3.02±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
CAY10685 is a cell-active analog of the lysine acetyltransferase inhibitor CPTH2 that contains an alkyne moiety for use in click chemistry reactions. Its ability to inhibit N-acetyltransferase 10 activity has been used to modulate chromatin organization in order to study changes in nuclear architecture associated with cancer and certain laminopathies. | [Uses]
CAY10685 is a cell-active analog of the lysine acetyltransferase inhibitor CPTH2 that contains an alkyne moiety for use in click chemistry reactions. | [References]
[1] DELPHINE LARRIEU. Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells[J]. Science, 2014, 344 6183. DOI: 10.1126/science.1252651 |
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| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
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