| Identification | Back Directory | [Name]
5-FAM Me-tetrazine | [CAS]
1619222-85-3 | [Synonyms]
5-FAM Me-tetrazine
6-Methyl-Tetrazine-5-FAM
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxamide, 3',6'-dihydroxy-N-[[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl]-3-oxo- | [Molecular Formula]
C31H21N5O6 | [MOL File]
1619222-85-3.mol | [Molecular Weight]
559.53 |
| Hazard Information | Back Directory | [Description]
Tetrazine (methyltetrazine) derivative of fluorescein, pure 5-isomer.
Tetrazines are reactive heterodiene components for [4+2] inverse electron demand Diels-Alder reaction (ied-DA) with strained cycloalkenes (trans-cyclooctenes, cyclopropenes). This reaction is also called TCO (tetrazine-cyclooctene) ligation. The reaction is among the fastest bioconjugation reactions. | [Uses]
6-Methyl-Tetrazine-5-FAM, is a Fluorescent dye, that can be used for various labeling applications in chemistry. (Abs/Em = 492/517 nm) | [Abs/Em Maxima]
492/517 nm | [Fluoresene quantum yield]
0.93 | [Extinction Coefficient]
74000 | [CF260]
0.22 | [CF280]
0.17 |
|
|