| Identification | Back Directory | [Name]
1H-Indazole-5-carboxamide, N-(3,4-difluorophenyl)- | [CAS]
1619884-65-9 | [Synonyms]
PSB1434
PSB-1434
PSB 1434
1H-Indazole-5-carboxamide, N-(3,4-difluorophenyl)-
N-(3,4-difluorophenyl)-1H-indazole-5-carboxamide (NTZ-1034) | [Molecular Formula]
C14H9F2N3O | [MDL Number]
MFCD31629803 | [MOL File]
1619884-65-9.mol | [Molecular Weight]
273.24 |
| Chemical Properties | Back Directory | [Boiling point ]
365.1±37.0 °C(Predicted) | [density ]
1.498±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
11.49±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
PSB-1434 is a potent, selective, competitive, and reversible inhibitor of monoamine oxidase B (MAO-B). | [Uses]
PSB-1434 is an inhibitor for monoamine oxidase B (MAO-B), with an IC50 of 1.59 nM[1]. | [IC 50]
MAO-B: 1.59 nM (IC50) | [References]
[1] Tzvetkov NT, et al., Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency. J Med Chem. 2014 Aug 14;57(15):6679-703. DOI:10.1021/jm500729a |
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