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1628113-16-5

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1628113-16-5 Structure

1628113-16-5 Structure
IdentificationBack Directory
[Name]

2,5-Dioxo-1-(4-(pyridin-2-yldisulfanyl)butanoyloxy)pyrrolidine-3-sulfonic acid
[CAS]

1628113-16-5
[Synonyms]

SPDB-sulfo
2,5-Dioxo-1-(4-(pyridin-2-yldisulfanyl)butanoyloxy)pyrrolidine-3-sulfonic acid
[Molecular Formula]

C13H14N2O7S3
[MDL Number]

MFCD28556911
[MOL File]

1628113-16-5.mol
[Molecular Weight]

406.45
Chemical PropertiesBack Directory
[density ]

1.66±0.1 g/cm3(Predicted)
[pka]

-0.04±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) [1].
[IC 50]

Disulfide Cleavable Linker
[References]

[1] Tinya Abrams, et al. ANTIBODY DRUG CONUGATES. US20140271688A1.
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