| Identification | Back Directory | [Name]
PKR-IN-2 | [CAS]
1628428-01-2 | [Synonyms]
AG519
PKR-IN-2
PKR inhibitor 2
pyruvate,PKRIN2,Pyruvate Kinase,kinase,PKR IN 2,inhibit,Inhibitor,deficiency
N-(4-(4-hydroxy-4-isobutylpiperidine-1-carbonyl)phenyl)quinoxaline-5-sulfonamide
5-Quinoxalinesulfonamide, N-[4-[[4-hydroxy-4-(2-methylpropyl)-1-piperidinyl]carbonyl]phenyl]- | [Molecular Formula]
C24H28N4O4S | [MDL Number]
MFCD29472293 | [MOL File]
1628428-01-2.mol | [Molecular Weight]
468.57 |
| Chemical Properties | Back Directory | [Boiling point ]
681.5±65.0 °C(Predicted) | [density ]
1.336±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 50 mg/mL (106.71 mM) | [form ]
Solid | [pka]
6.11±0.50(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
PKR activator 3 is a pyruvate kinase isoform PKR activator extracted from patent WO2014139144A1, compound 160. PKR activator 3 can be used for the research of PKR function related diseases, including cancer, diabetes, obesity, autoimmune disorders, and benign prostatic hyperplasia[1]. | [References]
[1] Popovici-Muller, et al. Preparation of N-(piperidinecarbonylphenyl) sulfonamide compounds as pyruvate kinase modulators. From PCT Int. Appl. (2014), WO2014139144A1 20140918. |
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| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
|