| Identification | More | [Name]
FMOC-MET(O2)-OH | [CAS]
163437-14-7 | [Synonyms]
FMOC-MET(O2)-OH
FMOC-L-MET(O2)-OH
FMOC-METHIONINE(O2)-OH
FMOC-L-METHIONINE-SULFONE
N-FMoc-L-Methionine sulfone, 98%
N-ALPHA-FMOC-L-METHIONINE-SULFONE
Fmoc-L-methionine sulfone≥ 98% (HPLC)
FMoc-Met(O)2-OH FMoc-L-Methionine sulfone
(9H-Fluoren-9-yl)MethOxy]Carbonyl Met(O2)-OH
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-METHIONINE SULFONE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-METHIONINESULFON
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-METHIONINESULFONE
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylsulfonylbutanoic acid
(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(methylsulfonyl)butanoic acid
(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methanesulfonylbutanoic acid
Butanoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-(methylsulfonyl)-, (2S)- | [Molecular Formula]
C20H21NO6S | [MDL Number]
MFCD00153361 | [Molecular Weight]
403.45 | [MOL File]
163437-14-7.mol |
| Chemical Properties | Back Directory | [Boiling point ]
709.5±60.0 °C(Predicted) | [density ]
1.359 | [storage temp. ]
Store at RT. | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
3.52±0.10(Predicted) | [color ]
White | [Major Application]
peptide synthesis | [InChI]
InChI=1S/C20H21NO6S/c1-28(25,26)11-10-18(19(22)23)21-20(24)27-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m0/s1 | [InChIKey]
KJLKPACOHZKRFM-SFHVURJKSA-N | [SMILES]
C(O)(=O)[C@@H](NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)CCS(C)(=O)=O | [CAS DataBase Reference]
163437-14-7(CAS DataBase Reference) |
| Questions and Answers (Q&A) | Back Directory | [Description]
FMOC-Met (O2)-OH is the N-alpha protected form of L-methionine mediated by FMOC group (9-Fluorenylmethyloxycarbonyl). It is useful to act as a building block in peptide synthesis. For example, it, as well as its derivative Tbfmoc-Met-OH can be used as a building block for the solid phase synthesis of ubiquitin C-hydrazide. It can also be used for synthesizing some novel cyclic peptides with pharmacological effects such as treatment of inflammatory disease.
| [References]
http://www.sigmaaldrich.com/technical-documents/articles/chemfiles/natural-amino-acid.html
https://www.iris-biotech.de/de/faa1490/Anderson, S. N., et al. "Microarrayed compound screening (microARCS) to identify activators and inhibitors of AMP-activated protein kinase."Journal of Biomolecular Screening 9.2(2004):112-121.
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http://www.google.com/patents/US6511961
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