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1638504-66-1

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1638504-66-1 Structure

1638504-66-1 Structure
IdentificationBack Directory
[Name]

HIV-1 integrase inhibitor 4
[CAS]

1638504-66-1
[Synonyms]

HIV-1 integrase inhibitor 4
1,8-Naphthyridine-3-carboxamide, 4-amino-N-[(2,4-difluorophenyl)methyl]-1,2-dihydro-1-hydroxy-2-oxo-6-[2-(phenylsulfonyl)ethyl]-
[Molecular Formula]

C24H20F2N4O5S
[MDL Number]

MFCD31619265
[MOL File]

1638504-66-1.mol
[Molecular Weight]

514.5
Chemical PropertiesBack Directory
[density ]

1.517±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

6.80±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM.
[References]

[1] Zhao XZ, et al. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant MutantIntegrases. ACS Chem Biol. 2016 Apr 15;11(4):1074-81. DOI:10.1021/acschembio.5b00948
1638504-66-1 suppliers list
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Telephone: 15911056312
Website: www.bio-fount.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Shanghai Yiyan Biotechnology Co. , Ltd.  
Telephone: 021-69985186 13611928337
Website: www.chemicalbook.com/ShowSupplierProductsList1691458/0_EN.htm
Company Name: Shandong Dayou Pharmaceutical Research and Development Co., Ltd.  
Telephone: hanfangpharma@126.com 15165037910
Website:
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