ChemicalBook--->CAS DataBase List--->1639208-54-0

1639208-54-0

1639208-54-0 Structure

1639208-54-0 Structure
IdentificationBack Directory
[Name]

Valbenazine tosylate
[CAS]

1639208-54-0
[Synonyms]

NBI-98854 Tosylate
Valbenazine tosylate
Valbenazine Ditosylate
[Molecular Formula]

C31H46N2O7S
[MDL Number]

MFCD32696930
[MOL File]

1639208-54-0.mol
[Molecular Weight]

590.78
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 100 mg/mL (131.07 mM);;
Hazard InformationBack Directory
[Uses]

Valbenazine tosylate (NBI-98854 tosylate) is a vesicular monoamine transporter 2 (VMAT2) inhibitor with the Ki of 110-190 nM[1].
[in vivo]

Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response in rats[1].

[storage]

Store at -20°C
[References]

[1] Dimitri E Grigoriadis, et al. Pharmacologic Characterization of Valbenazine (NBI-98854) and Its Metabolites. J Pharmacol Exp Ther. 2017 Jun;361(3):454-461. DOI:10.1124/jpet.116.239160
Spectrum DetailBack Directory
[Spectrum Detail]

Valbenazine tosylate(1639208-54-0)MS
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