| Identification | Back Directory | [Name]
MC-Val-Cit-PAB-dimethylDNA31 | [CAS]
1639352-06-9 | [Synonyms]
MC-Val-Cit-PAB-dimethylDNA31 | [Molecular Formula]
C78H101N10O19+ | [MDL Number]
MFCD32201118 | [MOL File]
1639352-06-9.mol | [Molecular Weight]
1482.72 |
| Hazard Information | Back Directory | [Uses]
MC-Val-Cit-PAB-dimethylDNA31 is a agent-linker conjugate for ADC with potent antitumor activity by using dimethylDNA31, linked via the ADC linker MC-Val-Cit-PAB. DimethylDNA31 has effective bactericidal activity against persisters and stationary-phase S. aureus. | [IC 50]
Traditional Cytotoxic Agents | [References]
[1] Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119. DOI:10.1038/nchem.2635 |
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