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166977-24-8

166977-24-8 Structure

166977-24-8 Structure
IdentificationBack Directory
[Name]

Benzoic acid, 4-[[(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)carbonyl]amino]-
[CAS]

166977-24-8
[Synonyms]

BMS185411
BMS-185411
BMS 185411
UNII-XD1FZ690NR
Benzoic acid, 4-[[(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)carbonyl]amino]-
[Molecular Formula]

C26H23NO3
[MOL File]

166977-24-8.mol
[Molecular Weight]

397.47
Chemical PropertiesBack Directory
[Boiling point ]

529.1±50.0 °C(Predicted)
[density ]

1.236±0.06 g/cm3(Predicted)
[pka]

4.27±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

BMS-185411 is a selective retinoic acid receptor alpha (RARα) antagonist, with an IC50 value of 140 nM[1].
[References]

[1] Md Abdullah Al Noman, et al. Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception. Eur J Med Chem. 2023 Dec 5:261:115821. DOI:10.1016/j.ejmech.2023.115821
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