| Identification | More | [Name]
Cbz-D-Valine | [CAS]
1685-33-2 | [Synonyms]
BENZYLOXYCARBONYL-D-VALINE
CBZ-D-VAL
CBZ-D-VAL-OH
N-ALPHA-BENZYLOXYCARBONYL-D-VALINE
N-ALPHA-CARBOBENZOXY D-VALINE
N-ALPHA-CBZ-D-VALINE
N-BENZYLOXYCARBONYL-D-VALINE
N-CARBOBENZOXY-D-VALINE
N-CBZ-D-VALINE
Z-D-VALINE
Z-D-VAL-OH
CBZ-D-VALINE
N-CBZ-D-VAL-OH
(S)-2-(BENZYLOXYCARBONYLAMINO)-3-METHYLBUTANOIC ACID (CBZ-D-VAL-OH )
N-Benzyloxycarbonyl-D-valine, 98+%
Z-D-VALINE extrapure
(2R)-2-(Benzyloxycarbonylamino)-3-methylbutyric acid
(R)-2-(Benzyloxycarbonylamino)-3-methylbutyric acid
(R)-2-[[(Benzyloxy)carbonyl]amino]-3-methylbutanoic acid | [EINECS(EC#)]
1533716-785-6 | [Molecular Formula]
C13H17NO4 | [MDL Number]
MFCD00065703 | [Molecular Weight]
251.28 | [MOL File]
1685-33-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
58-60°C | [Boiling point ]
432.6±38.0 °C(Predicted) | [density ]
1.182±0.06 g/cm3(Predicted) | [refractive index ]
4 ° (C=2, AcOH) | [storage temp. ]
Store at RT. | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder to crystal | [pka]
4.00±0.10(Predicted) | [color ]
White to Almost white | [BRN ]
2056616 | [InChI]
InChI=1S/C13H17NO4/c1-9(2)11(12(15)16)14-13(17)18-8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3,(H,14,17)(H,15,16)/t11-/m1/s1 | [InChIKey]
CANZBRDGRHNSGZ-LLVKDONJSA-N | [SMILES]
C(O)(=O)[C@@H](C(C)C)NC(OCC1=CC=CC=C1)=O | [CAS DataBase Reference]
1685-33-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [HS Code ]
29225090 |
| Hazard Information | Back Directory | [Uses]
N-Cbz-D-valine is the N-Cbz-protected form of D-Valine (V094200). D-Valine (an isomer of the essential amino acid L-Valine [V094205])exhibited inhibitory effects on fibroblasts that contaminated mammalian kidney cultures, allowing for selective growth epithelial cells. D-Valine is also known for its presence in the structure of Actinomycin D, an antitumour drug. D-Valine is naturally synthesized by Streptomyces antibioticus. | [Synthesis]
At 0°C, 10 mmol of D-valine was dissolved in 50 ml of a saturated solution of sodium bicarbonate (NaHCO3) at this temperature to obtain the dissolved solution, and the reaction was carried out with 11 mmol of benzyl chloroformate added dropwise to the dis |
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