| Identification | Back Directory | [Name]
2-Pyrazinecarboxamide, 5-[[[(3,4-difluorophenyl)sulfonyl]amino]methyl]-6-methyl-N-[(2-methyl-5-thiazolyl)methyl]- | [CAS]
1688685-29-1 | [Synonyms]
2-Pyrazinecarboxamide, 5-[[[(3,4-difluorophenyl)sulfonyl]amino]methyl]-6-methyl-N-[(2-methyl-5-thiazolyl)methyl]- | [Molecular Formula]
C18H17F2N5O3S2 | [MOL File]
1688685-29-1.mol | [Molecular Weight]
453.49 |
| Hazard Information | Back Directory | [Description]
MPX-007 is a potent NMDA inhibitor. MPX-007 inhibit GluN2A-containing NMDA receptors expressed in HEK cells with IC50s of 27 nM. MPX-007 offer highly selective pharmacological tools to probe GluN2A physiology and involvement in neuropsychiatric and developmental disorders. | [Uses]
MPX-007 is a GluN2A antagonist (IC50: 27 nM). MPX-007 is a tools to probe GluN2A physiology, and to study neuropsychiatric and developmental disorders[1]. | [References]
[1] Volkmann RA, et al. MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit. PLoS One. 2016 Feb 1;11(2):e0148129. DOI:10.1371/journal.pone.0148129 |
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| Company Name: |
A2B Chem LLC
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| Tel: |
010 |
| Website: |
www.a2bchem.com |
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