| Identification | Back Directory | [Name]
BMS-901715 | [CAS]
1699861-37-4 | [Synonyms]
BMS-901715
BMS901715,BMS 901715
Phenol, 3-[[5-[(4-amino-1-piperidinyl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-5-[2-(1-methylethyl)-2H-tetrazol-5-yl]- | [Molecular Formula]
C22H28N10O | [MDL Number]
MFCD34567217 | [MOL File]
1699861-37-4.mol | [Molecular Weight]
448.52 |
| Hazard Information | Back Directory | [Uses]
BMS-901715 is a potent and selective adapter protein-2 associated kinase 1 (AAK1) inhibitor with an IC50 of 3.3 nM[1][2]. | [References]
[1] Kostich W, et al. Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86. DOI:10.1124/jpet.116.235333
[2] Carolyn Diane Dzierba, et al. Pyrrolotriazine kinase inhibitors. WO2015054358A1. |
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