| Identification | Back Directory | [Name]
(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid | [CAS]
171336-76-8 | [Synonyms]
(2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid
(2R,4R)-4-amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid
2,4-Pyrrolidinedicarboxylic acid, 4-amino-1-(phenylmethyl)-, (2R,4R)- | [Molecular Formula]
C13H16N2O4 | [MDL Number]
MFCD00946238 | [MOL File]
171336-76-8.mol | [Molecular Weight]
264.28 |
| Hazard Information | Back Directory | [Uses]
1-Benzyl-APDC acts as an agonist for mGluR6, with an EC50 of 20 μM in CHO cells. 1-Benzyl-APDC is a weak antagonist of mGluR2, with an IC50 of 200 μM[1]. | [IC 50]
mGlu6: 20 μM (EC50); mGluR2: 200 μM (IC50) | [References]
[1] J K Mukhopadhyaya, et al. Synthesis of N(1)-substituted analogues of (2R,4R)-4-amino-pyrrolidine-2,4-dicarboxylic acid as agonists, partial agonists, and antagonists of group II metabotropic glutamate receptors. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1919-24. DOI:10.1016/s0960-894x(01)00329-8 |
|
| Company Name: |
TargetMol
|
| Telephone: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
|