ChemicalBook--->CAS DataBase List--->17467-15-1

17467-15-1

17467-15-1 Structure

17467-15-1 Structure
IdentificationMore
[Name]

5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE
[CAS]

17467-15-1
[Synonyms]

1,2,4-THIADIAZOL-5-AMINE, 3-PHENYL-
3-PHENYL-1,2,4-THIADIAZOL-5-AMINE
5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE
TIMTEC-BB SBB005511
4-thiadiazol-5-amine,3-phenyl-2
3-phenyl-1,2,4-thiadiazol-5-ylamine
3-Phenyl-1,2,4-triazol-5-ylamine
5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE 99%
[EINECS(EC#)]

241-485-0
[Molecular Formula]

C8H7N3S
[MDL Number]

MFCD00003159
[Molecular Weight]

177.23
[MOL File]

17467-15-1.mol
Chemical PropertiesBack Directory
[Appearance]

LIGHT BROWNISH FINE CRYSTALLINE POWDER
[Melting point ]

152-156 °C
[density ]

1.2353 (rough estimate)
[refractive index ]

1.5700 (estimate)
[storage temp. ]

2-8°C
[form ]

powder
[color ]

White
[InChI]

InChI=1S/C8H7N3S/c9-8-10-7(11-12-8)6-4-2-1-3-5-6/h1-5H,(H2,9,10,11)
[InChIKey]

OYAHSBDYBOBAAQ-UHFFFAOYSA-N
[SMILES]

S1C(N)=NC(C2=CC=CC=C2)=N1
[CAS DataBase Reference]

17467-15-1(CAS DataBase Reference)
[EPA Substance Registry System]

1,2,4-Thiadiazol-5-amine, 3-phenyl- (17467-15-1)
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
[Safety Statements ]

S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S22:Do not breathe dust .
[TSCA ]

TSCA listed
[HazardClass ]

IRRITANT
[HS Code ]

29341000
Hazard InformationBack Directory
[Description]

5-Amino-3-phenyl-1,2,4-thiadiazole is an important organic synthetic reagent with remarkable reactivity and stability and has been used in the synthesis of a variety of heterocyclic compounds including 1,2,4-triazol-3-ylphenyls, derivatives of 2-aryl-5-amino-thiadiazole, 5-amino-1,2,4-thiadiazol-3-phenyls, and 5 -amino-1,2,4-thiadiazole-3-phenyl-3-methyl derivatives. It is also used in the synthesis of polymers such as poly(5-amino-3-phenyl-1,2,4-thiadiazole). In addition, 5-amino-3-phenyl-1,2,4-thiadiazole is an inhibitor of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). The compound inhibits the release of pro-inflammatory cytokines such as tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β).
[Chemical Properties]

LIGHT BROWNISH FINE CRYSTALLINE POWDER
[Uses]

3-Phenyl-1,2,4-thiadiazol-5-amine is used as a reactant in the preparation of thiazole and thiadiazole derivatives as potent and selective human adenosine A3 receptor antagonists.
Spectrum DetailBack Directory
[Spectrum Detail]

5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)MS
5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)1HNMR
5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)13CNMR
5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)IR1
5-AMINO-3-PHENYL-1,2,4-THIADIAZOLE(17467-15-1)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

5-Amino-3-phenyl-1,2,4-thiadiazole, 99%(17467-15-1)
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