| Identification | More | [Name]
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate | [CAS]
175137-27-6 | [Synonyms]
BUTTPARK 46\18-97
METHYL 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE
Methyl2-chloro-4-(trifluoromethyl)pyrimidine-5-
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-
Methyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate ,97% | [Molecular Formula]
C7H4ClF3N2O2 | [MDL Number]
MFCD00068146 | [Molecular Weight]
240.57 | [MOL File]
175137-27-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
253-254 °C | [Boiling point ]
76-78°C 0,5mm | [density ]
1.491 | [refractive index ]
n20/D1.468 | [Fp ]
>110℃ | [storage temp. ]
2-8°C | [form ]
liquid | [pka]
-5.70±0.29(Predicted) | [Appearance]
Colorless to light yellow Liquid | [Detection Methods]
HPLC | [InChI]
1S/C7H4ClF3N2O2/c1-15-5(14)3-2-12-6(8)13-4(3)7(9,10)11/h2H,1H3 | [InChIKey]
VLUBJYUOPNGBOQ-UHFFFAOYSA-N | [SMILES]
COC(=O)c1cnc(Cl)nc1C(F)(F)F | [CAS DataBase Reference]
175137-27-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS06 | [Signal word ]
Danger | [Hazard statements ]
H301-H315-H319-H335 | [Precautionary statements ]
P301+P310+P330-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) . | [RIDADR ]
UN 2810 6.1 / PGIII | [WGK Germany ]
3 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
2933599590 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
Methyl 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate is used in the synthetic preparation and discovery of 2-[(2,4-Dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide (G931520) which is a highly selective CB2 receptor agonist for the treatment of inflammatory and neuropathic pain. |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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