| Identification | Back Directory | [Name]
(S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)thiophene-2-carboxaMide | [CAS]
1770812-37-7 | [Synonyms]
Rivaroxaban-4
Rivaroxaban ImpIV
Rivaroxaban EP Impurity H
Rivaroxaban Dichloro Impurity
Rivaroxaban Impurity 4(4,5-Dichloro Rivaroxaban)
(S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)thiophene-2-carboxaMide
4,5-Dichloro-N-[[2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
2-Thiophenecarboxamide, 4,5-dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-
Rivaroxaban Impurity 20/4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide | [Molecular Formula]
C19H17Cl2N3O5S | [MDL Number]
MFCD28347519 | [MOL File]
1770812-37-7.mol | [Molecular Weight]
470.33 |
| Chemical Properties | Back Directory | [Boiling point ]
718.5±60.0 °C(Predicted) | [density ]
1.514±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12.52±0.46(Predicted) | [color ]
White to Off-White | [Major Application]
pharmaceutical (small molecule) | [InChI]
1S/C19H17Cl2N3O5S/c20-14-7-15(30-17(14)21)18(26)22-8-13-9-24(19(27)29-13)12-3-1-11(2-4-12)23-5-6-28-10-16(23)25/h1-4,7,13H,5-6,8-10H2,(H,22,26)/t13-/m0/s1 | [InChIKey]
CCLKYVZRBJQFLK-ZDUSSCGKSA-N | [SMILES]
[s]1c(c(cc1C(=O)NC[C@@H]2OC(=O)N(C2)c3ccc(cc3)N4CCOCC4=O)Cl)Cl |
| Hazard Information | Back Directory | [Uses]
4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor. |
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