1770812-37-7
中文名称
(S)-4,5-二氯-N-((2-氧代-3-(4-(3-氧代吗啉代)苯基)噁唑烷-5-基)甲基)噻吩-2-甲酰胺
英文名称
(S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)thiophene-2-carboxaMide
CAS
1770812-37-7
分子式
C19H17Cl2N3O5S
分子量
470.33
MOL 文件
1770812-37-7.mol
更新日期
2026/01/15 15:41:23
1770812-37-7 结构式
基本信息
中文别名
利伐沙班杂质IV利伐沙班二氯杂质
4,5-二氯化合物
利伐沙班杂质H (EP)
4,5-二氯化合物
利伐沙班杂质D
(S)-4,5-二氯-N-((2-氧代-3-(4-(3-氧代吗啉代)苯基)噁唑烷-5-基)甲基)噻吩-2-甲酰胺
4,5-二氯-N-[[(5S)-2-氧代-3-[4-(3-氧代-4-吗啉基)苯基]-5-恶唑烷基]甲基]-2-噻吩甲酰胺
英文别名
Rivaroxaban-4Rivaroxaban ImpIV
Rivaroxaban EP Impurity H
Rivaroxaban Dichloro Impurity
Rivaroxaban Impurity 4(4,5-Dichloro Rivaroxaban)
(S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)thiophene-2-carboxaMide
4,5-Dichloro-N-[[2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
2-Thiophenecarboxamide, 4,5-dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-
Rivaroxaban Impurity 20/4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
所属类别
分析化学：药典标准品和杂质标准品物理化学性质
沸点718.5±60.0 °C(Predicted)
密度1.514±0.06 g/cm3(Predicted)
储存条件2-8°C
溶解度DMSO (Slightly), Methanol (Slightly)
酸度系数(pKa)12.52±0.46(Predicted)
形态Solid
颜色White to Off-White
主要应用pharmaceutical (small molecule)
InChI1S/C19H17Cl2N3O5S/c20-14-7-15(30-17(14)21)18(26)22-8-13-9-24(19(27)29-13)12-3-1-11(2-4-12)23-5-6-28-10-16(23)25/h1-4,7,13H,5-6,8-10H2,(H,22,26)/t13-/m0/s1
InChIKeyCCLKYVZRBJQFLK-ZDUSSCGKSA-N
SMILES[s]1c(c(cc1C(=O)NC[C@@H]2OC(=O)N(C2)c3ccc(cc3)N4CCOCC4=O)Cl)Cl
