| Identification | More | [Name]
Clonixin | [CAS]
17737-65-4 | [Synonyms]
2-[(3-chloro-2-methylphenyl)amino]-3-pyridinecarboxylic acid
CLONIXIC ACID
CLONIXIN
3-Pyridinecarboxylic acid, 2-[(3-chloro-2-methylphenyl)amino]-
CLONIXIC ACID (CLONIXIN)
2-(3-CHLORO-2-METHYLPHENYLAMINO)NICOTINIC ACID
2-(3-Chloro-2-methylanilino)pyridine-3-carboxylic acid
2-(3-Chloro-o-toluidino)nicotinic acid
Sch-10304 | [EINECS(EC#)]
241-730-1 | [Molecular Formula]
C13H11ClN2O2 | [MDL Number]
MFCD00864292 | [Molecular Weight]
262.69 | [MOL File]
17737-65-4.mol |
| Chemical Properties | Back Directory | [Melting point ]
233-235° | [Boiling point ]
410.2±45.0 °C(Predicted) | [density ]
1.3230 (rough estimate) | [refractive index ]
1.5270 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
DMSO: soluble15mg/mL, clear | [form ]
powder | [pka]
1.69±0.36(Predicted) | [color ]
white to beige | [Merck ]
14,2392 | [CAS DataBase Reference]
17737-65-4(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
20/21/22 | [Safety Statements ]
36/37 | [WGK Germany ]
3 | [RTECS ]
QT0960000 | [HS Code ]
2933.39.9200 | [Toxicity]
LD50 in male mice, rats (mg/kg): 415, 335 orally; 198, 148 i.p.; 296, 325 s.c. (Tanaka) |
| Hazard Information | Back Directory | [Uses]
Analgesic. | [Uses]
Clonixin is a non-steroidal anti-inflammatory drug. It also has analgesic, antipyretic, and platelet-inhibitory actions. The compound has been reported to block prostaglandin synthesis, and to block inward calcium currents. | [Definition]
ChEBI: A pyridinemonocarboxylic acid that is nicotinic acid substituted at position 2 by a (2-methyl-3-chlorophenyl)amino group. Used (as its lysine salt) for treatment of renal colic, muscular pain and moderately severe migraine attacks. | [Biological Activity]
Clonixin is a non steroidal anti inflammatory drug (NSAID) with analgesic properties. The compound has been reported to block prostaglandin synthesisand to block inward calcium currents. |
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