| Identification | Back Directory | [Name]
3-(allylsulphinyl)-L-alanine | [CAS]
17795-26-5 | [Synonyms]
ACSO
rac-Alliin
(+/-)-L-Alliin
Einecs 241-773-6
3-(allylsulphinyl)-L-alanine
(+/-)-L-ALLIIN, >=90% (HPLC)
Alliin (Mixture of DiastereoMers)
L-Alanine, 3-(2-propenylsulfinyl)-
L-Cysteine, S-2-propen-1-yl-, S-oxide
(2R)-2-amino-3-(prop-2-ene-1-sulfinyl)propanoic acid | [EINECS(EC#)]
241-773-6 | [Molecular Formula]
C6H11NO3S | [MDL Number]
MFCD00151977 | [MOL File]
17795-26-5.mol | [Molecular Weight]
177.22 |
| Chemical Properties | Back Directory | [Boiling point ]
416.1±45.0 °C(Predicted) | [density ]
1.354±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
1.88±0.10(Predicted) | [color ]
White to light yellow | [BRN ]
1724805 |
| Hazard Information | Back Directory | [Description]
Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor. Alliin exhibits anti-cancer, anti-microbial, anti-hypertensive, cardioprotective, and anti-oxidant activities. It has been shown to inhibit squalene monooxygenase, a rate-limiting step in the downstream pathway of cholesterol biosynthesis, with an IC50 value of 120 μM. | [Uses]
rac-Alliin has shown notable preventive effects on cardiac marker enzymes and lipids in isoproterenol-induced myocardial injury. rac-Alliin is also known to exhibit anticancer, antimicrobial, antihypertensive, antioxidant activities. | [Definition]
ChEBI: 3-(Allylsulphinyl)-L-alanine is a L-alpha-amino acid. | [General Description]
Alliin is the precursor of allicin. | [Biochem/physiol Actions]
S-Allyl-L-cysteine ((±)-L-Alliin) (SAC) may be used to study its potential as an anti-Alzheimer′s factor. SAC has been shown to increase cell proliferation and neuroblast differentiation by increasing 5-HT(1A) and provide antioxidative benefit to neurons and synapses. |
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