ChemicalBook--->CAS DataBase List--->1781882-72-1

1781882-72-1

1781882-72-1 Structure

1781882-72-1 Structure
IdentificationBack Directory
[Name]

SB 747651A dihydrochloride
[CAS]

1781882-72-1
[Synonyms]

SB 747651A dihydrochloride
SB747651A Dihydrochloride,SB 747651A Dihydrochloride
2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-4-piperidinyl-1H-imidazo[4,5-c]pyridine-7-methanamine dihydrochloride
[Molecular Formula]

C16H23ClN8O
[MDL Number]

MFCD26792571
[MOL File]

1781882-72-1.mol
[Molecular Weight]

378.87
Chemical PropertiesBack Directory
[solubility ]

Soluble to 50 mM in water and to 50 mM in DMSO
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

SB 747651A Dihydrochloride is a useful intermediate.
[in vivo]

SB747651A (3 mg/kg; intrascrotal injection) dihydrochloride results in increased neutrophil adhesion 3.5~4.5 hours following stimulation with CXCL2 as compared to the effect of CXCL2[3].
SB-747651A (3 mg/kg; i.p.) dihydrochloride affects neutrophil extravasation by increasing neutrophil emigration only at 3 and 4 hours in mouse peritonitis model of acute inflammation[3].

Animal Model:Male C57BL/6N mice (8~16 weeks)[3]
Dosage:3 mg/kg
Administration:Intrascrotal injection
Result:Resulted in increased neutrophil adhesion 3.5~4.5 hours following stimulation with CXCL2 as compared to the effect of CXCL2.
[storage]

Desiccate at RT
Spectrum DetailBack Directory
[Spectrum Detail]

SB 747651A dihydrochloride(1781882-72-1)1HNMR
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